Bacillus coagulans youyue
1. Regulate the balance of microflora in the animal intestine
Bacillus coagulans is a facultative anaerobic bacteria that grows and reproduces quickly under aerobic conditions, and quickly deprives oxygen. It limits the colonization of pathogenic bacteria in the intestine faster through nutritional competition and positional competition, and better prevents the reproduction of good hydrogen pathogens. In the process of oxygen deprivation, it produces its proprietary antibacterial peptide-a lectin completely deprives oxygen to form an anaerobic environment; under anaerobic conditions, the bacteria will immediately turn to ferment glucose to produce lactic acid.
2. produce antibacterial/bactericidal substances
A. antibacterial peptide-lectin. The alpha helix structure composed of 44 amino acids has a strong damaging effect on the cell membrane of G-bacteria and directly plays a role similar to the treatment of enteritis. Lectin has certain tolerance to temperature, acid and alkali, and is not destroyed by amylase and lipase that are often added in feed.
B. lactic acid-has a broad-spectrum inhibitory effect on many kinds of bacteria.
C. a mixture of some low molecular weight primary amines.
Pathogenic bacteria that can be inhibited/killed: coliform, Salmonella, Shigella, Proteus, Leuconostoc, Listeria, Micrococcus, and some pseudomonas.
3. Improve feed conversion rate and supplement nutrition
A. Bacillus coagulans secretes amylase, hemicellulase, lipase, protease, pectinase, glucanase, cellulase and other digestive enzymes in the process of animal intestinal reproduction.
B. Bacillus coagulans produces vitamins, amino acids, short-chain fatty acids, etc. in the process of animal intestinal reproduction. Such as VB2, VB6, folic acid, niacin and so on.
4. Prevention of constipation in animals
A. secrete short-chain fatty acids and amino acids to strengthen intestinal peristalsis;
B. The spore surface protein of Bacillus coagulans has a certain degree of water absorption and water retention, which helps to moisten the intestines and lax;
C. The secretion of lactic acid and other fatty acids into the animal’s intestine is beneficial to repair the damaged intestinal mucosa and restore intestinal function.
5. Enhance immune function
Promote the increase in the number of T cells and B cells in the animal body, enhanced phagocytosis, faster humoral and cellular immune activity, and improved disease resistance.
1. Cell shape: rod-shaped, with blunt ends at both ends; similar to the cell shape and size of the bacteria produced by our Bs-1, but slightly smaller. The main difference between spores and lichens is that they have a small tail and no flagella when they form mature sporangia.
2. Gram-positive bacteria, optimum growth temperature: 45℃-50℃; optimum pH value: pH6.6-7.0.
3. Homo-lactic acid fermentation, fermenting glucose does not produce CO2 gas, only L-lactic acid, not acetic acid.
1. The spores are very resistant to high temperatures;
A. under dry heat conditions: 120℃ 60 minutes drop by an order of magnitude;
B. under damp and hot conditions: 90℃ 60 minutes drop by an order of magnitude;
C, complete feed pelleting: 90 or less, less than 5 minutes, spore mortality rate is less than 5%, more suitable for pelleting than Bacillus subtilis.
2. Storage durability:
After the feed is produced, the spores will not die during the storage period specified in the feed. If it is mixed into a liquid state, its activity can still be measured after one year of storage at pH 4.5, and it can still be stored for one month when placed in 8% NaCl solution.
3. Resistance to gastric acid and bile:
It can tolerate the condition that the strong acid with pH value 1.4 and the bile salt concentration reach 3.0% (the bile salt concentration in the pig intestine is only 0.03%-0.3%);
4. It is a facultative anaerobic bacteria that multiplies quickly in animals with a doubling time of 30 minutes; under the condition of low dissolved oxygen concentration in the intestinal tract of animals, it can synthesize a large amount of lactic acid and lectin.
Livestock, aquatic products, ruminants:
≥20 billion cfu/g, 50-100g/T compound feed
≥50 billion cfu/g, 25-50g/T compound feed